About VariantMatcher

VariantMatcher is a freely accessible web site developed with support from the Baylor-Hopkins Center for Mendelian Genomics (BHCMG) as part of the Centers for Mendelian Genomics network.

VariantMatcher is designed to enable connections between patients, their families, clinicians and researchers from around the world who share an interest in the same variant or variants. The principal goal for making VariantMatcher available is to help solve 'unsolved' exomes. This may be done with cases from research or clinical sources.

The site allows individuals to post a genomic coordinate of interest and will connect these individuals to participants of the BHCMG with interest in a variant in the same position. Users create an account and submit genomic coordinate(s) of interest. The match is done automatically. When a match occurs, the submitters and the BHCMG participant will receive an email notification. Follow-up is at the discretion of both parties.

If a match is not identified at the time of submission, the genomic coordinate(s) of interest will not continue to be queried as the information is not stored in the database.

VariantMatcher adheres to strict safety and privacy protocols. Users must register and be approved to use the site. The database is not searchable and does not collect identifiable data. Users may not access the full database.

See the Frequently Asked Questions (FAQs) for Additional information.

Use of VariantMatcher is governed by the End User License Agreement (EULA).